Bruce C. Allen

Independent Consultant in Chapel Hill, NC

Contact

101 Corbin Hill Circle
Chapel Hill, NC 27514
bruce_allen@verizon.net
919-401-5385 (voice)
919-401-5384 (fax)

Bio

Bruce Allen has 27 years of experience related to human and environmental health and safety. He has expertise as a biomathematician involved in risk assessment, modeling, statistical analysis, and clinical trials, having worked for a variety of government and private clients. Mr. Allen’s primary interest is in the quantitative aspects of risk analysis, reflecting his experience with dose-response analysis; with the statistical appraisal of data, models, and modeling results; and with developing rigorous approaches to decision making in risk assessment contexts. His expertise in dose-response analysis extends to the modeling, including biologically motivated modeling, of cancer, noncancer, and genotoxic endpoints as well as genomics data. Mr. Allen's statistical expertise includes computer-intensive approaches – such as Monte Carlo simulation, bootstrap analysis, and Markov chain Monte Carlo approaches for Bayesian analyses – as well as other techniques for uncertainty analyses, data quality objectives, quality control/assurance, statistical analyses for site risk assessments, and analysis of clinical trials data. The products of his analyses have resulted in expert testimony, technical reports, presentations at national meetings, and peer-reviewed publications.

Education

• Master of Biomathematics, Biomathematics (Statistics minor), North Carolina State University, 1980.

• B.A., Philosophy, University of Washington, Honors, Summa Cum Laude, 1978

• B.S., Mathematics, University of Washington, Honors, Summa Cum Laude, 1978

Experience

• 1980-1983. Department of Biostatistics, University of North Carolina; Lipid Research Clinics Program.

• 1983-1997. KS Crump Group, ICF Kaiser.

• 1997-2000. RAS Associates, Independent Consultant.

• 2000-2002. KS Crump Group, ICF Kaiser.

• 2002-2005. Environ International Corporation.

• 2006-present. Bruce Allen Consulting, Independent Consultant

Previous Clients

• American Chemistry Council

• Attorneys (several)

• California EPA

• Ciba-Geigy

• CIIT

• EPRI

• Food Standards Agency, Scotland

• Lockheed Martin Information Technology

• Piedmont Pharmaceuticals

• Southern Pacific Railroad

• Toxicology Excellence for Risk Assessment (TERA)

• U.S. Air Force

• U.S. Environmental Protection Agency

• U.S. Occupational Safety and Health Administration

Publications and Reports (Topics)

• Bayesian Statistical Analyses

• Benchmark Dose Estimation

• Biomarkers – Use in Inferring Exposure Levels

• Bootstrap Statistical Analyses of Real-Time Exposure Monitoring

• Cancer Risk Assessment Methods

• Categorical Data Analysis

• Clinical Trials Design and Analysis

• Developmental Toxicity Dose-Response

• Epidemiological Data Analyses

• Fisheries Monitoring

• Genomics Dose-Response

• Genotoxicity Modeling and Dose-Response

• Markov Chain Monte Carlo Applications

• Physiologically Based Pharmacokinetic Modeling

• Simulation Analyses using Monte Carlo Approaches

• Software Evaluation and Testing

• Survey Data Design and Analysis

• Uncertainty/Sensitivity Analyses

Publication Sources (Peer-Reviewed Journals)

• American Statistician

• Chemosphere

• Comments in Toxicology

• Environmental Health Perspectives

• Fundamental and Applied Toxicology

• Health Physics

• Journal of Chronic Diseases

• Journal of Toxicology and Environmental Health

• Occupational Hygiene

• Regulatory Toxicology and Pharmacology

• Risk Analysis

• Science for the Total Environment

• Toxicological Sciences

• Toxicology and Applied Pharmacology

• Toxicology and Industrial Health

• Toxicology Letters